Detoxification and Biotransformation


The Problem


Like any process involving construction and demolition, our bodies build and remove substances constantly. The removal process is called biotransformation or detoxification. The liver is the primary organ of biotransformation. It has two distinct processes:


Phase 1, by way of the actions of the Cytochrome P450 system


Phase 2, which involves the alteration of these intermediary products to water-soluble substances. The kidneys, colonm and sweat glands then excrete these inactivated toxins.


The circumstances of modern life have a tremendous impact on our detoxification systems. For starters, there is the overload of toxic substances we acquire from the environment. Thousands of novel chemicals have been introduced into the environment with inadequate safety testing, forcing us to try to detoxify substances that our systems are not designed to process. Our genetics have not been able to keep pace with the growing demands imposed on our detoxification pathways by overwhelming environmental challenges.


Adding even more stress to our already overburdened detox systems, our modern food supply does not provide the proper nutrients in sufficient quantities to support detoxification, while overwhelming our bodies with preservatives, genetically modified foods, and antibiotics. Other stressors such as excessive exercise, use of medication, inadequate sleep, and alcohol consumption add to the burden.


The IMNY Solution


Supporting biotransformation can alleviate symptoms such as fatigue, headaches, malaise, and depression. We need to look at every step in the process.


First, by addressing the sources of toxins we can ease the burden on the liver. Diet is central to this treatment process. Eliminate the foods that are laden with chemicals you can’t pronounce, preservatives and coloring agents, genetically modified ingredients, and nutrient-deprived processed foods. We recommend a diet of real foods with varied colors for their phytonutrient content: garlic, beets, broccoli sprouts, organic apples, broccoli, fermented foods, as well as substantial mounts of dietary fibers... combined with the elimination of sugar, gluten, soy, and cow's-milk dairy products. Adequate water consumption is needed to keep kidney function optimal.


Next, we remove unnecessary medications, alcohol, and environmental toxins that place greater demands on detoxification pathways. We address other factors such as chronic infections, mold exposure, heavy metals, and stress – all of which increase the production of substances that require biotransformation.


Detoxification programs come in various forms. A two-week elimination diet combined with liver-supporting nutrients is one approach. Another is the use of a “push-catch” detox program that enhances liver function while sequestering the toxins that are excreted in the bile with binders such as activated charcoal, chlorophyll, bentonite clay, cholestyramine, and soluble fiber. These binders push toxins through the liver into bile and then captures them in the stool to ensure their elimination.


The use of supplements such as N Acetyl cysteine, liposomal glutathione (the body’s main detoxifier), phytonutrient blends, vitamin C, and milk thistle will provide the liver with what it needs for optimal function.


Finally, a series of IV treatments containing IV glutathione, vitamins, and minerals will jump-start the process for those who are particularly toxic.